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The Dorset Formulary has been developed in associations with
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Poole Hospital NHS Foundation Trust
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust
 
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
Notes:

Chapter review date:

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02.11  Expand sub section  Antifibrinolytic drugs and haemostatics
02.11  Expand sub section  Blood-related products
Antihaemophilic Factor/von Willebrand Factor Complex
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Formulary
Red
High Cost Medicine
Non pharmacy item please contact blood bank for details and availability.

Recombinant Von Willebrand Factor not routinely commissioned by NHS England. As per IFR approval. 
   
Antithrombin III
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Formulary
Red
High Cost Medicine
Non pharmacy item please contact blood bank for details and availability.

Commissioned by NHS England as per BCSH Guidelines. 
   
Factor IX Fraction, Dried
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Formulary
Red
High Cost Medicine
Non pharmacy item please contact blood bank for details and availability.

Commissioned by NHS England, as per BCSH guidelines.

Available from CSL Behring (Mononine®), BPL (Replenine®-VF, Dried Factor IX Fraction), Grifols (AlphaNine®), Biotest UK (Haemonine®)

Note Preparation of recombinant coagulation factor IX (nonacog alfa) available from Pfizer (BeneFIX®)

 
   
Factor VII
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Formulary
Red
High Cost Medicine
Non pharmacy item please contact blood bank for details and availability.

Commissioned by NHS England as per BCSH Guidelines.

 
   
Factor VIIa (Recombinant) - eptacog alfa (activated) (NovoSeven®)
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Formulary
Red
High Cost Medicine
Non pharmacy item please contact blood bank for details and availability.
DCHFT: Currently held by Pharmacy (Nov 2014).

Commissioned by NHS England as per BCSH Guidelines.

 
Link  DCHFT: Emergency reversal of anti-coagulation guideline (including use of Octaplex and NovoSeven)
   
Factor VIII Fc Fusion Protein
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Formulary
Red
High Cost Medicine
Non-pharmacy item. Please contact blood bank for details and availability.
Commissioned by NHS England as per BCSH Guidelines.

 
   
Factor VIII Fraction, Dried
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Formulary
Red
High Cost Medicine
Commissioned by NHS England as per BCSH Guidelines.

Available from Biotest UK (Haemoctin®), CSL Behring (Haemate® P), BPL (Optivate®, High Purity Factor VIII and von Willebrand factor concentrate; 8Y®), Grifols (Alphanate®; Fanhdi®), Octapharma (Octanate®; Wilate®); Haemoctin®, Optivate®, Fanhdi®, and Octanate® are not indicated for use in von Willebrand’s disease

Note Preparation of recombinant human coagulation factor VIII (octocog alfa) available from CSL Behring (Helixate® NexGen), Baxter (Advate®), Bayer (Kogenate® Bayer); preparation of recombinant human coagulation factor VIII (moroctocog alfa) available from Wyeth (ReFacto AF®); octocog alfa and moroctocog alfa are not indicated for use in von Willebrand's disease

 
   
Factor VIII Inhibitor Bypassing Fraction (FEIBA®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Red
High Cost Medicine
Non-pharmacy item. Please contact blood bank for details and availability.

Commissioned by NHS England as per BCSH Guidelines.

 
   
Factor XIII Fraction, Dried (Fibrogammin® P)
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Formulary
Red
High Cost Medicine
Non-pharmacy item. Please contact blood bank for details and availability.
Commissioned by NHS England as per BCSH Guidelines.

 
   
Fibrinogen (Riastap®)
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Formulary
Red
High Cost Medicine
Non-pharmacy item. Please contact blood bank for details and availability.
Commissioned by NHS England as per BCSH Guidelines.

 
   
Fresh Frozen Plasma
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Formulary
Red
Available from Regional Blood Transfusion Services

Note: A preparation of solvent/detergent treated human plasma (frozen) from pooled donors is available from Octapharma (OctaplasLG®)

 
   
Protein C Concentrate (Ceprotin®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Red
High Cost Medicine
See commissioning and funding guidance from NHS England. 
   
Prothrombin complex (Beriplex® P/N, Octaplex®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Red
High Cost Medicine
Commissioned by NHS England as per BCSH Guidelines.
Blood-related product.

DCHFT: Held by Pharmacy (Nov 2014).

 
Link  DCHFT: Emergency reversal of anti-coagulation guideline (including use of Octaplex and NovoSeven)
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

May be initiated, stabilised and maintained in primary, secondary or tertiary care  

Amber

Amber drug - without shared care  

Amber SCG

Amber drug - with shared care guideline  

Red

For secondary or tertiary care initiation and long-term maintenance of prescribing  

Black

Not recommended  

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