Dorset Formulary


	Dorset The Dorset Formulary has been developed in associations with NHS Dorset Clinical Commissioning Group Dorset County Hospital NHS Foundation Trust Dorset Healthcare University NHS Foundation Trust University Hospitals Dorset NHS Foundation Trust

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Formulary Chapter 4: Central nervous system - Full Chapter

Notes:

Chapter review date:

Chapter Links...

Management of Fibromyalgia November 2017

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04.02.02

Antipsychotic depot injections

Flupentixol Decanoate

Formulary

Depot injection

Hospital initiation
Option based on NICE guidance and licence

200mg/ml low volume injection is more expensive so reserve for higher dose prescriptions (>250mg)

Fluphenazine Decanoate

Formulary

Hospital initiation
Option based on NICE guidance and licence

Discontinued in March 2018. Not to be prescribed for new patients

Discontinuation of fluphenazine decanoate depot injection - advice for prescribers

Haloperidol
(Haldol Decanoate^®)

Formulary

Hospital initiation
Option based on NICE guidance and licence

Zuclopenthixol Decanoate (Clopixol^® and Clopixol^® Conc)

Formulary

Hospital initiation
Option based on NICE guidance and licence

Aripiprazole intramuscular injection (Abilify Maintena^®)

Formulary

For the maintenance of adult patients with schizophrenia who have responded to oral aripiprazole but who are non-compliant.

see guidelines for the use of aripiprazole long acting injections

Olanzapine Embonate (ZypAdhera^®)

Formulary

Hospital use only
See olanzapine LAI guidelines
Can be considered as a treatment option for psychoses with appropriate risk management arrangements

Paliperidone prolonged release suspension for injection (Xeplion^®)

Formulary

Hospital Use only

See paliperidone long-acting injection prescribing guidelines.

Paliperidone LAI guideline

Risperidone LAI (Risperdal Consta^®)

Formulary

no new patients to intitiate risperidone long acting injection
see paliperidone LAI

Paliperidone 3 monthly -prolonged release suspension for injection (Trevicta ®)

Formulary

3 monthly injections for patients on a stable dose of paliperidone LAI for a minimum of 6 months.

New requests for Trevicta must be approved by Dorset Healthcare Medicines Management Team

Guidance on the Use of Antipsychotics for Conditions other than Schizophrenia

NICE CG103: Delirium

NICE CG178: Schizophrenia

QTc Prolongation: Guidance for Mental Health Prescribers (Dorset CCG, 2019)

UKMI Q&A: Neuroleptic malignant syndrome - which drugs can cause it?

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Non Formulary Items

Flupentixol Decanoate (Depixol^® Conc.)

Non Formulary

Flupentixol Decanoate (Depixol^® Low Volume)

Non Formulary

Fluphenazine Decanoate (Modecate^®)

Non Formulary

2018 Discontinuation of fluphenazine decanoate depot injection - advice for prescribers

Fluphenazine Decanoate (Modecate^® Concentrate)

Non Formulary

2018 Discontinuation of fluphenazine decanoate depot injection - advice for prescribers

Zuclopenthixol Decanoate (Clopixol^® Conc.)

Non Formulary

Key

	Notes
	Section Title (top level)
	Section Title (sub level)
	First Choice item
	Non Formulary section
	Restricted Drug
	Unlicensed
	Display tracking information
	Link to adult BNF
	Link to children's BNF
	Link to SPCs

	Cytotoxic Drug
	Controlled Drug
	High Cost Medicine
	Cancer Drugs Fund
	NHS England
	Homecare
	CCG

Traffic Light Status Information

Status	Description
	May be initiated, stabilised and maintained in primary, secondary or tertiary care
	Amber drug - without shared care
	Amber drug - with shared care guideline
	For secondary or tertiary care initiation and long-term maintenance of prescribing
	Not recommended