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The Dorset Formulary has been developed in associations with
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 Formulary Chapter 4: Central nervous system - Full Chapter
Notes:

Chapter review date:

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04.04  Expand sub section  CNS stimulants and other drugs used for attention deficit hyperactivity disorder
Controlled Drug Lisdexamfetamine (Elvanse®)
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Second Choice
Amber SCG

Second/third line option for adults, younger patients and those unable to swallow tablets as part of a comprehensive treatment in line with NICE NG87.

Refer to shared care guidance.

DCHFT: Restricted Item  Consultant psychiatrist only. 

 
 
Atomoxetine (Strattera®)
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Formulary
Amber SCG
Capsules.
For use in ADHD in accordance with recommendations made by NICE (TA98) and locally agreed treatment algorithm and shared care guideline.

DCHFT: Restricted Item  Consultant psychiatrist only. 
 
Controlled Drug Methylphenidate
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Formulary
Amber SCG

Tablets, modified release capsules and tablets.
Use as per NICE NG87 and local shared care guidelines - children and adults.

All modified release preparations can be prescribed under shared care agreement.

 

Branded generics bioequivalent to Concerta are now available. These include Delmosart, Matoride, Xaggitin and Xenidate. Prescribers are asked to consider the most cost effective option taking into consideration the strengths and release profiles available. Prescribers should specify the specific name of the preparation and these should not be switched.

Relative costs of bioequivalent MR generics:


Methylphenidate brand


Cost per 30 tablets


 


18mg


27mg


36mg


54mg


Concerta XL tab


£31.19


36.81


42.45


73.62


Matoride XL tablets, Xenidate XL tablets, Delmosart XL tablets and Xaggitin XL tablets have all been granted marketing authorisation on the bioequivalence to Concerta XL tablets as the licensed reference product as opposed to clinical studies.


Matoride XL tablets and Xenidate XL are presented as biconvex round tablets whereas Concerta XL, Delmosart XL and Xaggitin XL are capsule shaped tablets of a similar size to the bioequivalent products.


 


Delmosart tab


£15.57


18.39


21.21


36.79


Xaggitin XL tab


£15.58


18.40


21.22


36.80


Xenidate XL tab


£18.39


18.39


21.21


36.79


Matoride XL tab


£15.58


-


21.22


36.80

 

Prices from Shared Care guideline, July 2019
 
DCHFT: Modified release formulations are second line when compliance with standard release form is a significant problem.

 
Link  UKMI Q&A: Methylphenidate for adults with ADHD
 
Guanfacine (Intuniv®)
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Formulary
Amber SCG

in line with NICE NG87 diagnosis and local shared care guidance

 
 
Modafinil (Provigil®)
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Formulary
Amber
Tertiary care initiation only 
 
Controlled Drug Dexamfetamine
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Formulary
Amber SCG
Tablets.
For ADHD in children. Refer to local shared care guideline.

DCHFT: Restricted Item  Consultant psychiatrist only. 
 
04.04  Expand sub section  Cocaine
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

May be initiated, stabilised and maintained in primary, secondary or tertiary care  

Amber

Amber drug - without shared care  

Amber SCG

Amber drug - with shared care guideline  

Red

For secondary or tertiary care initiation and long-term maintenance of prescribing  

Black

Not recommended  

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