netFormulary Dorset NHS
The Dorset Formulary has been developed in associations with
NHS Dorset Clinical Commissioning Group
Dorset County Hospital NHS Foundation Trust
Dorset Healthcare University NHS Foundation Trust
Poole Hospital NHS Foundation Trust
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust
 
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
Notes:

Updated in accordance with CDF and NICE guidance May 2018. For latest CDF list click here.

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08.03.04.02  Expand sub section  Prostate cancer and gonadorelin analogues
08.03.04.02  Expand sub section  Gonadorelin analogues
08.03.04.02  Expand sub section  Anti-androgens
Bicalutamide
View adult BNF View SPC online  Track Changes
Formulary
Amber SCG

50mg - for use in advanced/metastatic disease.
150mg - for locally advanced disease as an alternative to LHRH and also as neo-adjuvant/adjuvant treatment prior to and after radiotherapy in accordance with locally agreed criteria and shared care guideline.

 

 

There is currently a supply problem with generic 50mg bicalutamide tablets which is expected to be resolved by the end of January 2018. GPs are requested to issue a 1 month prescription for the Casodex brand in the interim as this remains available at present.

 
Link  Shared care guideline bicalutamide
   
Cyproterone Acetate
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Formulary
Amber
 
   
Enzalutamide (Xtandi)
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Formulary
Red
High Cost Medicine
In accordance with NICE TAs.

NICE TA 316: for metastatic hormone‐relapsed prostate cancer previously treated with a docetaxel‐containing regimen.

NICE TA 377: for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated (from April 16)
 
Link  Enzalutamide for metastatic hormonerelapsed prostate cancer previously treated with a docetaxel]containing regimen (TA316)
Link  NICE TA 377: Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Flutamide
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Formulary
Amber
 
   
Abiraterone acetate (Zytiga )
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Formulary
Red
High Cost Medicine
BlueTeq

For use in accordance with NICE TA259 and TA387 reccomendations.

 
Link  NICE TA259: Abiraterone for castration resistant prostate cancer
Link  NICE TA387: Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
08.03.04.02  Expand sub section  Gonadotrophin-releasing hormone antagonists
08.03.04.02  Expand sub section  Radiopharmaceuticals to top
 ....
 Non Formulary Items
Flutamide  (Drogenil®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

May be initiated, stabilised and maintained in primary, secondary or tertiary care  

Amber

Amber drug - without shared care  

Amber SCG

Amber drug - with shared care guideline  

Red

For secondary or tertiary care initiation and long-term maintenance of prescribing  

Black

Not recommended  

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